Poetry: Critique of Genetic Engineering

Posted by Chengde Chen *

“Genetic engineering technology is designed to enable genes to cross species 
barriers.” – Martin Khor, New diseases as viruses break species barriers 


Genetic engineering has a million benefits,

While I have only one reason against it.

But, any number multiplying a zero becomes a zero.

Science is supposed to support human existence;

If genes are written by all historical conditions of nature,

Isn’t quoting them out of context man outlawing himself?
 


The temperature on the Earth’s surface is within ±50ºC

A very small range in the grand thermometer of the universe,

But just the home for us – the creature of 37ºC – to survive.

Believers marvel at God’s arrangement, yet it’s only nature.

All existing species are adapters to this condition;

Those not, either never had a chance, or have been eliminated.

 

Should God, seized by a whim, play at “planet engineering”

Rearranging the order of the solar system, what would happen?

If Earth moved one step inwards to the position of Venus,

The mighty 480ºC would evaporate us into clouds.

If Earth moved one step outwards to the position of Mars,

The minus 140ºC would cast us into super-ice.



Earth is in our genes.

Genes are nature’s vertical memory and horizontal logic.

The process of adapting and eliminating carves all specifications.

The billions of codes are billions of doors and locks without keys,

Shutting out foreign viruses with DNA incompatibility

So we don’t catch cats’ flu, nor do dogs get our hepatitis.
 


Yet, manufactured genes come suddenly

Sharing no responsibility of history but short-circuiting species.

When transgenic pig organs are implanted into humans, 

Pig viruses also leap over millions of years to join us.

To gain medical benefits by dismantling the species barriers, 

It’s self-disarming to the bone or tying oneself up to WMD?
 


The biological world is a self-contained all-dimensional computer;

Messing up one sequence could throw the whole system into chaos,

Which is asking God to restart His creation all over!

So He’d rather we mess about with the planets than modify genes.

“If you must,” He may say, “modify Mine first to have a GM god 

To recreate the world, I’d need enhanced energy and perseverance.” 


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* Chengde Chen is the author of the philosophical poems collection: Five Themes of Today, Open Gate Press, London. chengde.chen@hotmail.com

Hearts and Minds: The Mystery of Consciousness

By Mary Monro

Despite the best efforts of scientists and philosophers over the centuries, no mechanism has been discovered that indicates how consciousness emerges in the brain. Descartes famously thought the soul resided in the pineal gland - but that was mainly because he couldn't think of any other purpose for it (It actually produces melatonin and guides sleeping patterns). But, 400 years on, perhaps we still need to think again about where consciousness might reside.

In recent years there has been a surge of interest in the gut brain, with its hundred million neurons and its freight of microbes, that influences every aspect of our being including mood and memory. If the gut might now be considered a possible source of consciousness what about other candidates?

After all, “Primary consciousness arises when cognitive processes are accompanied by perceptual, sensory and emotional experience” as Fritjof Capra and Pier Luigi Luisi put it in their book The Systems View of Life: A Unifying Vision (2014).  Reflective or higher-order consciousness includes self-awareness and anticipation.

There is another intelligent, organising, feeling, planning, responsive, communicating organ inside us – a body-wide-web lining our blood vessels. Vascular endothelium cells (VE for short) line every vessel from the heart to the smallest capillary, reaching into every part of the body. Vascular endothelium is the interface between the blood and the tissues, deciding what goes where through a combination of electrical, kinetic, mechanical and chemical signalling.

Laid out, the VE in a human body would be the size of a rugby pitch yet it weighs only one kilogram. Far from being simply wallpaper, recent research has shown it to be a lead actor in the management of the body, including the brain. It is believed that each of the sixty trillion cells of the VE is unique, each one exquisitely adapted to meet the needs of its immediate environment, whether that is in the deeply oxygen deprived depths of the kidney or the highly oxygenated gas exchange surface of the lung. William Aird, in a scholarly paper in 2007, describes vascular endothelium as 'a powerful organising principle in health and disease'.

The blood-brain barrier (usually abbreviated to BBB) protects the brain from molecules and cells in the blood that might damage neural tissue. The vascular endothelium forms the interface but it was previously thought to be a passive sieve, controlled by neurons. The BBB has now been renamed the ‘neuro-vascular unit’ as it has become clear that neural cells, pericytes (that back the endothelial cells) and the vascular endothelial cells all actively take part in managing this critical barrier. It is not known which of them is in charge.

Other researchers have sought to apply the Turing Test to the VE in the brain – the Turing Test being an evaluation of whether an information processing system is capable of intelligent, autonomous thought. Christopher Moore and Rosa Cao, argue that blood is drawn to particular areas of the brain by the VE, in advance of metabolic demand, where it stimulates and modulates neuronal function. So the brain is responder rather than activator. Who is doing the thinking? Is the body-wide-web (including the heart and its assistant the blood) gathering information from the body and the external environment to tell the brain what to do? How does it make decisions? What does this imply for consciousness?

In fact, long ago, Aristotle asserted that the vascular architecture in the embryo functions as a frame or model that shapes the body structure of the growing organism. Recent research bears this out, with the VE instructing and regulating organ differentiation and tissue remodelling, from the embryo to post-natal life.  The VE cells form before there is a heart and it is fluid flow that drives endothelial stem cells to trigger the development of the heart tube, vessels and blood cells. There is no brain, only a neural tube, at this stage.

Recent research has shown that blood vessels can direct the development of nerves or vice versa or they can each develop independently. So, embryologically, there is a case for saying that the VE is a decision making executive.

All this recalls a founding principle of osteopathy – which is that ‘the rule of the artery is supreme’.  This is a poetic, 19th century way of saying that disturbance to blood flow is at the root of disease. In his autobiography, published in 1908, Andrew Still remarks: ‘in the year 1874 I proclaimed that a disturbed artery marked the beginning to an hour and a minute when disease began to sow its seeds of destruction in the human body’.

Now, almost a century and a half on, we find that ‘endothelial activity is crucial to many if not all disease processes’, as K. S. Ramcharan put it in a recent paper entitled ‘The Endotheliome: A New Concept in Vascular Biology’ (published in Thrombosis Research in 2011). All this illustrates the importance of this seemingly humble tissue, upon whose health our mental and physical wellbeing depends. And if this structure acts consciously, then perhaps we should consider the possibility that all living cells act consciously.

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*Mary Monro Bsc (Hons) Ost, MSc Paed Ost, FSCCO is an Osteopath, based in Bath, United Kingdom.

Picture Post #18 A Somersault for the Suspension of Civilisation

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'Because things don’t appear to be the known thing; they aren’t what they seemed to be neither will they become what they might appear to become.'

Posted by Tessa den Uyl and Martin Cohen

Photo credit: students of  A Mundzuku Ka Hina, communications workshop. 

A life conditioned by the dictates of competition and consumption cannot but bring great social differences along in its train. When we ascribe symbolic values to a consumptive life, ideas will conform to ideals in which our moral duties are the rights of others on us.

The subtle way social disproportions are perceived as if a causa sui, something wherein the cause lies within itself creates a world of facts based upon competitive abstractions that endlessly rehearse on a Procrustean bed.

The salto (flying somersault) performed by the boy, who depends for his survival on a rubbish-dump, breaks with this gesture the conditioned life. What he breaks is to function, which means to think, alike a certain ‘life-design.’ His action shows the incompleteness of our relationships in an abstract world.

His jump is a jump into a space of non-facts.

In the suspension of the movement is the liberating being of lightness.